DNMT 1 maintains hypermethylation of CAG promoter specific region and prevents expression of exogenous gene in fat-1 transgenic sheep

Yang, CR; Shang, XY; Cheng, L; Yang, L; Liu, XF; Bai, CL; Wei, ZY; Hua, JL; Li, GP

Li, GP (reprint author), Inner Mongolia Univ, Res Ctr Lab Anim Sci, Hohhot, Peoples R China.

PLOS ONE, 2017; 12 (2):

Abstract

Methylation is an important issue in gene expression regulation and also in the fields of genetics and reproduction. In this study, we created fat-1 t......

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