A randomized phase II trial of CRLX101 in combination with bevacizumab versus standard of care in patients with advanced renal cell carcinoma

Voss, MH; Hussain, A; Vogelzang, N; Lee, JL; Keam, B; Rha, SY; Vaishampayan, U; Harris, WB; Richey, S; Randall, JM; Shaffer, D; Cohn, A; Crowell, T; Li, J; Senderowicz, A; Stone, E; Figlin, R; Motzer, RJ; Haas, NB; Hutson, T

Voss, MH (reprint author), Mem Sloan Kettering Canc Ctr, Dept Med, 353 East 68th St, New York, NY 10065 USA.

ANNALS OF ONCOLOGY, 2017; 28 (11): 2754

Abstract

Nanoparticle-drug conjugates enhance drug delivery to tumors. Gradual payload release inside cancer cells augments antitumor activity while reducing t......

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