Vemurafenib inhibits necroptosis in normal and pathological conditions as a RIPK1 antagonist

Sun, MY; Ma, XQ; Mu, W; Li, HA; Zhao, XM; Zhu, TF; Li, JQ; Yang, YL; Zhang, HB; Ba, Q; Wang, H

Ba, Q; Wang, H (通讯作者)，Shanghai Jiao Tong Univ, Ctr Single Cell Omics, Sch Publ Hlth, State Key Lab Syst Med Canc,Sch Med, Shanghai, Peoples R China.;Zhang, HB (通讯作者)，Chinese Acad Sci, Shanghai Inst Nutr & Hlth, CAS Key Lab Nutr Metab & Food Safety, Shanghai, Peoples R China.;Yang, YL (通讯作者)，Dalian Univ Technol, Sch Bioengn, Dalian, Peoples R China.

CELL DEATH & DISEASE, 2023; 14 (8):

Abstract

Necroptosis, a programmed cell death with necrotic-like morphology, has been recognized as an important driver in various inflammatory diseases. Inhib......

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