Complexation of NAC-Derived Peptide Ligands with the C-Terminus of alpha-Synuclein Accelerates Its Aggregation

Jha, NN; Ranganathan, S; Kumar, R; Mehra, S; Panigrahi, R; Navalkar, A; Ghosh, D; Kumar, A; Padinhateeri, R; Maji, SK

Maji, SK (reprint author), Indian Inst Technol, Dept Biosci & Bioengn, Bombay 400076, Maharashtra, India.

BIOCHEMISTRY, 2018; 57 (5): 791

Abstract

Aggregation of alpha-synuclein (alpha-Syn) into neurotoxic oligomers and amyloid fibrils is suggested to be the pathogenic mechanism for Parkinson's d......

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