Targeted a-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment-MedSci.cn

Targeted a-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment

Ertveldt, T; Krasniqi, A; Ceuppens, H; Puttemans, J; Dekempeneer, Y; De Jonghe, K; de Mey, W; Lecocq, Q; De Vlaeminck, Y; Awad, RM; Goyvaerts, C; De Veirman, K; Morgenstern, A; Bruchertseifer, F; Keyaerts, M; Devoogdt, N; D'Huyvetter, M; Breckpot, K

Breckpot, K (通讯作者)，Vrije Univ Brussel, Dept Biomed Sci, Lab Mol & Cellular Therapy, Brussels, Belgium.

Abstract

Targeted radionuclide therapy (TRT) using targeting moieties labeled with a-particle-emitting radionuclides (a-TRT) is an intensely investi-gated trea......

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Targeted a-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment

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