AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis

Chow, BSM; Kocan, M; Shen, M; Wang, Y; Han, L; Chew, JY; Wang, C; Bosnyak, S; Mirabito-Colafella, KM; Barsha, G; Wigg, B; Johnstone, EKM; Hossain, MA; Pfleger, KDG; Denton, KM; Widdop, RE; Summers, RJ; Bathgate, RAD; Hewitson, TD; Samuel, CS

Samuel, CS (reprint author), Monash Univ, Monash Biomed Discovery Inst, 9 Ancora Imparo Way, Clayton, Vic 3800, Australia.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2019; 30 (11): 2191

Abstract

Background Recombinant human relaxin-2 (serelaxin), which has organ-protective actions mediated via its cognate G protein?coupled receptor relaxin fam......

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