Substrate-Dependence of Competitive Nucleotide Pyrophosphatase/Phosphodiesterase1 (NPP1) Inhibitors

Lee, SY; Sarkar, S; Bhattarai, S; Namasivayam, V; De Jonghe, S; Stephan, H; Herdewijn, P; El-Tayeb, A; Muller, CE

Muller, CE (reprint author), Univ Bonn, Pharmaceut Chem 1, Inst Pharmaceut, PharmaCtr Bonn, Bonn, Germany.

FRONTIERS IN PHARMACOLOGY, 2017; 8 ( ):

Abstract

Nucleotide pyrophosphatase/phosphodiesterase type 1 (NPP1) is a membrane glycoprotein involved in the hydrolysis of extracellular nucleotides. Its maj......

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