Genkwadaphnin inhibits growth and invasion in hepatocellular carcinoma by blocking DHCR24-mediated cholesterol biosynthesis and lipid rafts formation

Wu, J; Guo, L; Qiu, XR; Ren, Y; Li, FF; Cui, W; Song, SJ

Song, SJ (corresponding author), Shenyang Pharmaceut Univ, Key Lab Computat Chem Nat Antitumor Drug Res & De, Shenyang 110016, Peoples R China.; Song, SJ (corresponding author), Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China.; Cui, W (corresponding author), Shenyang Pharmaceut Univ, Sch Life Sci & Biopharmaceut, Shenyang 110016, Peoples R China.

BRITISH JOURNAL OF CANCER, 2020; 123 (11): 1673

Abstract

Background The liver is the central organ for cholesterol homoeostasis, and its dysfunction might cause liver pathological alterations including hepat......

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