Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma

Tang, L; Zeng, J; Geng, PY; Fang, CN; Wang, Y; Sun, MJ; Wang, CS; Wang, J; Yin, PY; Hu, CX; Guo, L; Yu, JE; Gao, P; Li, EY; Zhuang, ZP; Xu, GW; Liu, Y

Xu, GW (reprint author), Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, 457 Zhongshan Rd, Dalian 116023, Peoples R China.; Liu, Y (reprint author), Chinese Acad Sci, Dalian Inst Chem Phys, 457 Zhongshan Rd, Dalian 116023, Pe

CLINICAL CANCER RESEARCH, 2018; 24 (2): 474

Abstract

Purpose: Metabolic reprogramming is frequently identified in hepatocellular carcinoma (HCC), which is the most common type of liver malignancy. The re......

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