Super-enhancer profiling identifies novel critical and targetable cancer survival gene LYL1 in pediatric acute myeloid leukemia

Fang, F; Lu, J; Sang, X; Tao, YF; Wang, JW; Zhang, ZM; Zhang, YP; Li, XL; Xie, Y; Wu, SY; Chu, XR; Li, G; Wu, D; Chen, YL; Yu, JJ; Jia, SQ; Feng, CX; Tian, YY; Li, ZH; Ling, J; Hu, SY; Pan, J

Pan, J (通讯作者)，Soochow Univ, Inst Pediat Res, Childrens Hosp, 92 Zhongnan St, Suzhou 215003, Peoples R China.;Hu, SY (通讯作者)，Soochow Univ, Dept Hematol, Childrens Hosp, 92 Zhongnan St, Suzhou 215003, Peoples R China.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2022; 41 (1):

Abstract

Background Acute myeloid leukemia (AML) is a myeloid neoplasm makes up 7.6% of hematopoietic malignancies. Super-enhancers (SEs) represent a special g......

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