S-Palmitoylation of Tyrosinase at Cysteine500 Regulates Melanogenesis

Niki, Y; Adachi, N; Fukata, M; Fukata, Y; Oku, S; Makino-Okamura, C; Takeuchi, S; Wakamatsu, K; Ito, S; Declercq, L; Yarosh, DB; Mammone, T; Nishigori, C; Saito, N; Ueyama, T

Ueyama, T (通讯作者),Kobe Univ, Biosignal Res Ctr, Lab Mol Pharmacol, Rokkodai Cho 1-1,Nada Ku, Kobe 6578501, Japan.

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023; 143 (2): 317

Abstract

Palmitoylation is a lipid modification involving the attachment of palmitic acid to a cysteine residue, thereby affecting protein function. We investi......

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