Pharmacogenomics of chloroquine and hydroxychloroquine: current evidence and future implications

Biswas, M; Sukasem, C

Sukasem, C (通讯作者)，Mahidol Univ, Ramathibodi Hosp, Div Pharmacogen & Personalized Med, Dept Pathol,Fac Med, Bangkok 10400, Thailand.;Sukasem, C (通讯作者)，Ramathibodi Hosp, Somdech Phra Debaratana Med Ctr SDMC, Lab Pharmacogen, Bangkok 10400, Thailand.;Sukasem, C (通讯作者)，Bumrungrad Int Hosp, Bumrungrad Genom Med Inst BGMI, Pharmacogen & Precis Med Clin, Bangkok 10110, Thailand.;Sukasem, C (通讯作者)，Burapha Univ, Fac Pharmaceut Sci, Saen Suk 20131, Chonburi, Thailand.;Sukasem, C (通讯作者)，Univ Liverpool, MRC Ctr Drug Safety Sci, Dept Pharmacol & Therapeut, Inst Syst Mol & Integrat Biol, Liverpool L69 3GL, England.

PHARMACOGENOMICS, 2023; 24 (15): 831

Abstract

As substrates of CYP2C8, CYP3A4/5 and CYP2D6, chloroquine's (CQ) and hydroxychloroquine's (HCQ) efficacy and safety may be affected by variants in the......

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