High-throughput screen identifies 5-HT receptor as a modulator of AR and a therapeutic target for prostate cancer

Itsumi, M; Shiota, M; Sekino, Y; Ushijima, M; Kashiwagi, E; Takeuchi, A; Inokuchi, J; Kajioka, S; Uchiumi, T; Eto, M

Shiota, M (corresponding author), Kyushu Univ, Grad Sch Med Sci, Dept Urol, Higashi Ku, 3-1-1 Maidashi, Fukuoka 8128582, Japan.

PROSTATE, 2020; 80 (11): 885

Abstract

Background Eradication of persistent androgen receptor (AR) activity in castration-resistant prostate cancer may be a promising strategy to overcome c......

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