GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity

Hauffe, R; Stein, V; Chudoba, C; Flore, T; Rath, M; Ritter, K; Schell, M; Wardelmann, K; Deubel, S; Kopp, JF; Schwarz, M; Kappert, K; Bluher, M; Schwerdtle, T; Kipp, AP; Kleinridders, A

JCI INSIGHT, 2020; 5 (11):

Abstract

Insulin receptor signaling is crucial for white adipose tissue (WAT) function. Consequently, lack of insulin receptor (1R) in WAT results in a diabete......

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