Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis

Miyabe, C; Miyabe, Y; Nagai, J; Miura, NN; Ohno, N; Chun, J; Tsubo, R; Ueda, H; Miyasaka, M; Miyasaka, N; Nanki, T

Nanki, T (reprint author), Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Dept Rheumatol, Tokyo, Japan.; Nanki, T (reprint author), Teikyo Univ, Dept Clin Res Med, Tokyo, Japan.; Nanki, T (reprint author), Toho Univ, Dept Internal Med, Div Rheumatol, Sch

ARTHRITIS RESEARCH & THERAPY, 2019; 21 (1):

Abstract

Background: Lysophosphatidic acid (LPA), generated by autotaxin (ATX), is a bioactive lipid mediator that binds to the receptors (LPA1-6), and serves ......

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