FLT3-ITD Allelic Burden and Acute Promyelocytic Leukemia Risk Stratification

Li, ANY; Kashanian, SM; Hambley, BC; Zacholski, K; Duong, VH; El Chaer, F; Holtzman, NG; Gojo, I; Webster, JA; Norsworthy, KJ; Smith, BD; DeZern, AE; Levis, MJ; Baer, MR; Kamangar, F; Ghiaur, G; Emadi, A

Emadi, A (corresponding author), Univ Maryland, Sch Med, Dept Med, Baltimore, MD 21201 USA.; Ghiaur, G (corresponding author), Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Baltimore, MD 21231 USA.; Emadi, A (corresponding author), Univ Maryland, Greenebaum Comprehens Canc Ctr, Baltimore, MD 21201 USA.; Emadi, A (corresponding author), Univ Maryland, Sch Med, Dept Pharmacol, Baltimore, MD 21201 USA.

BIOLOGY-BASEL, 2021; 10 (3):

Abstract

Simple Summary Around 12-38% of acute promyelocytic leukemia (APL) patients carry the FLT3-ITD mutation, which has been associated with several poor-p......

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