Bosentan attenuates sickle cell disease erythrocyte HbS polymerization and impaired deformability induced by endothelin-1

Teixeira-Alves, LR; Guimaraes-Nobre, CC; Mendonça-Reis, E; Miranda-Alves, L; Berto, C

Berto, C (通讯作者)，Univ Fed Rio de Janeiro, Grp Pesquisa Fisiol Eritroide GPFisEri, Campus Macae, Macae, RJ, Brazil.;Berto, C (通讯作者)，Univ Fed Rio de Janeiro, Fac Med, Programa Posgrad Radiol, Rio De Janeiro, RJ, Brazil.;Berto, C (通讯作者)，Univ Fed Rio de Janeiro, Lab Endocrinol Expt LEEx, Inst Ciencias Biomed, Rio De Janeiro, RJ, Brazil.;Berto, C (通讯作者)，Univ Fed Rio de Janeiro, Fac Farm, Campus Macae, Macae, RJ, Brazil.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2023; ():

Abstract

The effects of endothelin-1 (ET-1) on erythrocytes from sickle cell disease (SCD) patients have been described, but mechanisms of ET-1 regarding prima......

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