[I-131]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [I-131]MIBG in neuroblastoma

Kobayashi, M; Mizutani, A; Nishi, K; Muranaka, Y; Nishii, R; Shikano, N; Nakanishi, T; Tamai, I; Kleinerman, ES; Kawai, K

Kobayashi, M (corresponding author), Kanazawa Univ, Sch Hlth Sci, Inst Med Pharmaceut & Hlth Sci, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 9200942, Japan.

NUCLEAR MEDICINE AND BIOLOGY, 2020; 90-91 (): 49

Abstract

Introduction: I-131-labeled m-iodobenzylguanidine ([I-131]MIBG) has been used to treat neuroblastoma patients, but [I-131]MIBG may be immediately excr......

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