Revisiting Interleukin-12 as a Cancer Immunotherapy Agent

Berraondo, P; Etxeberria, I; Ponz-Sarvise, M; Melero, I

Melero, I (reprint author), CIMA, Ave Pio 12,55, Navarra 31008, Spain.; Melero, I (reprint author), CUN, Ave Pio 12,55, Navarra 31008, Spain.

CLINICAL CANCER RESEARCH, 2018; 24 (12): 2716

Abstract

IL12 antitumor activities are mediated by the activation of T and natural killer (NK) lymphocytes to produce IFNg. Systemically, recombinant IL12 has ......

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