Kill 'Em All: Efgartigimod Immunotherapy for Autoimmune Diseases

Bayry, J; Kaveri, SV

Bayry, J (reprint author), Univ Paris 05, INSERM, Equipe Immunopathol & Immunointervent Therapeut, Ctr Rech Cordeliers,Sorbonne Univ,Sorbonne Paris, F-75006 Paris, France.

TRENDS IN PHARMACOLOGICAL SCIENCES, 2018; 39 (11): 919

Abstract

Neonatal Fc receptors (FcRns) recycle IgGs by preventing their lysosome degradation. As this process also enhances half-life of pathogenic auto-IgG, i......

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