Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4(+) T-cell activation

Portal-Celhay, C; Tufariello, JM; Srivastava, S; Zahra, A; Klevorn, T; Grace, PS; Mehra, A; Park, HS; Ernst, JD; Jacobs, WR; Philips, JA

Philips, JA (reprint author), New York Univ, Sch Med, Div Infect Dis, Dept Med, New York, NY 10016 USA.; Jacobs, WR (reprint author), Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10461 USA.; Jacobs, WR (reprint author), Albert Einstein Co

NATURE MICROBIOLOGY, 2017; 2 (2):

Abstract

Mycobacterium tuberculosis (Mtb) establishes a persistent infection, despite inducing antigen-specific T-cell responses. Although T cells arrive at th......

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