Endothelial-specific deletion of autophagy-related 7 (ATG7) attenuates arterial thrombosis in mice

Yau, JW; Singh, KK; Hou, Y; Lei, X; Ramadan, A; Quan, A; Teoh, H; Kuebler, WM; Al-Omran, M; Yanagawa, B; Ni, HY; Verma, S

Verma, S (reprint author), St Michaels Hosp, Div Cardiac Surg, Suite 8-003,Bond Wing,30 Bond St, Toronto, ON M5B 1W8, Canada.; Singh, KK (reprint author), St Michaels Hosp, Div Vasc Surg, 209 Victoria St, Toronto, ON M5B 1T8, Canada.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2017; 154 (3): 978

Abstract

Background: Thrombosis persists as a leading cause of morbidity and mortality. Given that endothelial cells (ECs) play a central role in regulating th......

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