Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

Xia, JJ; Bai, H; Yan, B; Li, R; Shao, MH; Xiong, LW; Han, BH

Xiong, LW; Han, BH (reprint author), Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Dept Pulm Med, Shanghai 200030, Peoples R China.

ONCOTARGET, 2017; 8 (65): 108522

Abstract

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are widely applied to treat EGFR-mutant non-small cell lung cancer (NSCLC). BI......

Full Text Link