Enantioselective Nickel-Catalyzed Hydrocyanative Desymmetrization of Norbornene Derivatives

Sung, FL; Wang, T; Cheng, GJ; Fang, XJ

Fang, XJ (corresponding author), Shanghai Jiao Tong Univ, Shanghai Key Lab Mol Engn Chiral Drugs, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China.; Cheng, GJ (corresponding author), Chinese Univ Hong Kong Shenzhen, Sch Life & Hlth Sci, Warshel Inst Computat Biol, Shenzhen 518172, Peoples R China.; Cheng, GJ (corresponding author), Chinese Univ Hong Kong Shenzhen, Sch Life & Hlth Sci, Shenzhen Key Lab Steroid Drug Dev, Shenzhen 518172, Peoples R China.

ACS CATALYSIS, 2021; 11 (12): 7578

Abstract

A nickel-catalyzed enantioselective hydrocyanation of N-aryl 5-norbornene-endocis-2,3-dicarboximides was reported. This desymmetrization process allow......

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