Discovery of 2,4-diaminopyrimidine derivatives targeting p21-activated kinase 4: Biological evaluation and docking studies

Qin, QH; Wu, TX; Yin, WB; Sun, YX; Zhang, XY; Wang, RF; Guo, J; Zhao, DM; Cheng, MS

Zhao, DM (corresponding author), Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design Discovery, Minist Educ, Shenyang 110016, Peoples R China.

ARCHIV DER PHARMAZIE, 2020; 353 (10):

Abstract

In this study, novel 2,4-diaminopyrimidine derivatives targeting p21-activated kinase 4 (PAK4) were discovered and evaluated for their biological acti......

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