Advanced oxidation protein products downregulate CYP1A2 and CYP3A4 expression and activity via the NF-kappa B-mediated signaling pathway in vitro and in vivo

Xun, TR; Lin, ZF; Wang, XK; Zhan, X; Feng, HX; Gan, DN; Yang, XX

Yang, XX (corresponding author), Southern Med Univ, Shenzhen Hosp, Dept Pharm, Shenzhen, Peoples R China.; Yang, XX (corresponding author), Southern Med Univ, Nanfang Hosp, Dept Pharm, Guangzhou, Peoples R China.

LABORATORY INVESTIGATION, 2021; 101 (9): 1197

Abstract

Uremic toxin accumulation is one possible reason for alterations in hepatic drug metabolism in patients with chronic kidney disease (CKD). However, th......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索