USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy

Zhao, XB; Di, QQ; Yu, J; Quan, JZ; Xiao, Y; Zhu, HH; Li, HR; Ling, J; Chen, WL

Chen, WL (通讯作者),Shenzhen Univ, Dept Immunol, Guangdong Prov Key Lab Reg Immun & Dis, Sch Med, Shenzhen 518060, Peoples R China.

AUTOPHAGY, 2022; 18 (4): 891

Abstract

TBK1 (TANK-binding kinase 1) is an essential receptor protein required for the innate immune response, but the mechanisms underlying TBK1 stability, e......

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