Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment

Chini, M; Popplau, JA; Lindemann, C; Carol-Perdiguer, L; Hnida, M; Oberlander, V; Xu, XX; Ahlbeck, J; Bitzenhofer, SH; Mulert, C; Hanganu-Opatz, IL

Hanganu-Opatz, IL (corresponding author), Univ Med Ctr Hamburg Eppendorf, Inst Neuroanat, Dev Neurophysiol, D-20246 Hamburg, Germany.

NEURON, 2020; 105 (1): 60

Abstract

Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal networks. This dysfunction emerges during early dev......

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