Half-life extension using serum albumin-binding DARPin (R) domains

Steiner, D; Merz, FW; Sonderegger, I; Gulotti-Georgieva, M; Villemagne, D; Phillips, DJ; Forrer, P; Stumpp, MT; Zitt, C; Binz, HK

Binz, HK (reprint author), Mol Partners AG, Wagistr 14, CH-8952 Schlieren, Switzerland.

PROTEIN ENGINEERING DESIGN & SELECTION, 2017; 30 (9): 583

Abstract

A long systemic half-life is key for therapeutic proteins. To that end we have generated serum albumin-binding designed ankyrin repeat domains. These ......

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