Pilot trial of CRLX101 in patients with advanced, chemotherapy-refractory gastroesophageal cancer

Chao, J; Lin, J; Frankel, P; Clark, AJ; Wiley, DT; Garmey, E; Fakih, M; Lim, D; Chung, V; Luevanos, E; Eliasof, S; Davis, ME; Yen, Y

Chao, J (reprint author), City Hope Comprehens Canc Ctr, Dept Med Oncol & Therapeut Res, 1500 E Duarte Rd, Duarte, CA 91010 USA.

JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2017; 8 (6): 962

Abstract

Background: CRLX101 is an investigational nanoparticle-drug conjugate with a camptothecin payload. Preclinical evidence indicated preferential uptake ......

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