Erythroferrone inhibits the induction of hepcidin by BMP6

Arezes, J; Foy, N; McHugh, K; Sawant, A; Quinkert, D; Terraube, V; Brinth, A; Tam, M; LaVallie, ER; Taylor, S; Armitage, AE; Pasricha, SR; Cunningham, O; Lambert, M; Draper, SJ; Jasuja, R; Drakesmithm, H

Drakesmithm, H (reprint author), Univ Oxford, John Radcliffe Hosp, Headley Way, Oxford OX3 9DS, England.

BLOOD, 2018; 132 (14): 1473

Abstract

Decreased hepcidin mobilizes iron, which facilitates erythropoiesis, but excess iron is pathogenic in beta-thalassemia. Erythropoietin (EPO) enhances ......

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