One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model

Gooch, KE; Smith, TRF; Salguero, FJ; Fotheringham, SA; Watson, RJ; Dennis, MJ; Handley, A; Humphries, HE; Longet, S; Tipton, T; Sarfas, C; Sibley, L; Slack, GS; Rayner, E; Ryan, KA; Schultheis, K; Ramos, SJ; White, A; Charlton, S; Sharpe, SA; Gleeson, F; Humeau, LM; Hall, Y; Broderick, KE; Carroll, MW

Carroll, MW (corresponding author), Publ Hlth England PHE, Salisbury SP4 0JG, Wilts, England.; Broderick, KE (corresponding author), Inovio Pharmaceut Inc, 10480 Wateridge Circle, San Diego, CA 92121 USA.

VACCINE, 2021; 39 (34): 4885

Abstract

Safe and effective vaccines will provide essential medical countermeasures to tackle the COVID-19 pandemic. Here, we assessed the safety, immunogenici......

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