Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE(2) (Prostaglandin E-2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury

Hao, HF; Hu, S; Wan, Q; Xu, CS; Chen, H; Zhu, LY; Xu, ZY; Meng, J; Breyer, RM; Li, NL; Liu, DP; FitzGerald, GA; Wang, M

Wang, M (reprint author), Chinese Acad Med Sci, State Key Lab Cardiovasc Dis, Fuwai Hosp, Natl Ctr Cardiovasc Dis, 167 Beilishi Rd, Beijing 100037, Peoples R China.; Wang, M (reprint author), Peking Union Med Coll, 167 Beilishi Rd, Beijing 100037, Peoples

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018; 38 (5): 1115

Abstract

Objective Deletion of mPGES-1 (microsomal prostaglandin E synthase-1)an anti-inflammatory target alternative to COX (cyclooxygenase)-2attenuates injur......

Full Text Link