Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis

Togami, K; Chung, SS; Madan, V; Booth, CAG; Kenyon, CM; Cabal-Hierro, L; Taylor, J; Kim, SS; Griffin, GK; Ghandi, M; Li, J; Li, YY; Angelot-Delettre, F; Biichle, S; Seiler, M; Buonamici, S; Lovitch, SB; Louissaint, A; Morgan, EA; Jardin, F; Piccaluga, PP; Weinstock, DM; Hammerman, PS; Yang, H; Konopleva, M; Pemmaraju, N; Garnache-Ottou, F; Abdel-Wahab, O; Koeffler, HP; Lane, AA

Lane, AA (通讯作者)，Dana Farber Canc Inst, 450 Brookline Ave,Mayer 413, Boston, MA 02215 USA.

CANCER DISCOVERY, 2022; 12 (2): 522

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of plasmacytoid dendritic cells (pDC). BPDCN occurs at least three time......

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