IFN gamma induces epigenetic programming of human T-bet(hi) B cells and promotes TLR7/8 and IL-21 induced differentiation

Zumaquero, E; Stone, SL; Scharer, CD; Jenks, SA; Nellore, A; Mousseau, B; Rosal-Vela, A; Botta, D; Bradley, JE; Wojciechowski, W; Ptacek, T; Danila, MI; Edberg, JC; Bridges, SL; Kimberly, RP; Chatham, WW; Schoeb, TR; Rosenberg, AF; Boss, JM; Sanz, I;

Lund, FE (reprint author), Univ Alabama Birmingham, Dept Microbiol, Birmingham, AL 35294 USA.

ELIFE, 2019; 8 ():

Abstract

Although B cells expressing the IFN gamma R or the IFN gamma-inducible transcription factor T-bet promote autoimmunity in Systemic Lupus Erythematosus......

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