YAP Accelerates Notch-Driven Cholangiocarcinogenesis via mTORC1 in Mice

Lu, XJ; Peng, BG; Chen, G; Pes, MG; Ribback, S; Ament, C; Xu, HW; Pal, R; Rodrigues, PM; Banales, JM; Evert, M; Calvisi, DF; Chen, X; Fan, B; Wang, JX

Wang, JX (corresponding author), 11 EN 3rd Ring Rd, Beijing 100029, Peoples R China.; Fan, B (corresponding author), 52 Fucheng Rd, Beijing 100142, Peoples R China.

AMERICAN JOURNAL OF PATHOLOGY, 2021; 191 (9): 1651

Abstract

Intrahepatic cholangiocarcinoma (iCCA) is a lethal malignant neoplasm with limited therapeutic options. Previous studies have found that Notch1 overex......

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