Impact of the CYP2C19 genotype on voriconazole exposure in adults with invasive fungal infections

Hamadeh, IS; Klinker, KP; Borgert, SJ; Richards, AI; Li, WH; Mangal, N; Hiemenz, JW; Schmidt, S; Langaee, TY; Peloquin, CA; Johnson, JA; Cavallari, LH

Cavallari, LH (reprint author), Univ Florida, Ctr Pharmacogen, Dept Pharmacotherapy & Translat Res, POB 100486, Gainesville, FL 32610 USA.

PHARMACOGENETICS AND GENOMICS, 2017; 27 (5): 190

Abstract

ObjectivesVoriconazole, a first-line agent for the treatment of invasive fungal infections (IFIs), is metabolized by CYP2C19. A significant proportion......

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