EGFR Inhibition Overcomes Resistance to FGFR4 Inhibition and Potentiates FGFR4 Inhibitor Therapy in Hepatocellular Carcinoma

Shen, B; Shi, JP; Zhu, ZX; He, ZD; Liu, SY; Shi, W; Zhang, YX; Ying, HY; Wang, J; Xu, RF; Fang, F; Chang, HX; Chen, Z; Zhang, NN

Chen, Z; Zhang, NN (通讯作者)，Abbisko Therapeut Co Ltd, Bldg 3,898 Halei Rd, Shanghai 201203, Peoples R China.

MOLECULAR CANCER THERAPEUTICS, 2023; 22 (12): 1479

Abstract

Aberrant activation of the FGF19-FGFR4 signaling pathway plays an essential role in the tumorigenesis of hepatocellular carcinoma (HCC). As such, FGFR......

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