Discovery and SAR of Natural-Product-Inspired RXR Agonists with Heterodimer Selectivity to PPAR delta-RXR

Nakashima, K; Yamaguchi, E; Noritake, C; Mitsugi, Y; Goto, M; Hirai, T; Abe, N; Sakai, E; Oyama, M; Itoh, A; Inoue, M

Nakashima, K (corresponding author), Aichi Gakuin Univ, Sch Pharm, Lab Med Resources, Nagoya, Aichi 4648650, Japan.

ACS CHEMICAL BIOLOGY, 2020; 15 (6): 1526

Abstract

A known natural product, magnaldehyde B, was identified as an agonist of retinoid X receptor (RXR) alpha. Magnaldehyde B was isolated from Magnolia ob......

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