Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model

Xiao, J; Cai, T; Fang, YJ; Liu, R; Flores, JJ; Wang, WN; Gao, L; Liu, Y; Lu, Q; Tang, LH; Zhang, JH; Lu, HW; Tang, JP

Tang, JP (corresponding author), Loma Linda Univ, Dept Physiol & Pharmacol, Sch Med, Loma Linda, CA 92354 USA.; Lu, HW (corresponding author), Cent South Univ, Xiangya Hosp 3, Ctr Expt Med, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.

JOURNAL OF NEUROINFLAMMATION, 2021; 18 (1):

Abstract

Background Germinal matrix hemorrhage (GMH) is defined by the rupture of immature blood vessels in the germinal matrix, where subsequent hemorrhage en......

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