Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma

Da Via, MC; Dietrich, O; Truger, M; Arampatzi, P; Duell, J; Heidemeier, A; Zhou, X; Danhof, S; Kraus, S; Chatterjee, M; Meggendorfer, M; Twardziok, S; Goebeler, ME; Topp, MS; Hudecek, M; Prommersberger, S; Hege, K; Kaiser, S; Fuhr, V; Weinhold, N; Rosenwald, A; Erhard, F; Haferlach, C; Einsele, H; Kortum, KM; Saliba, AE; Rasche, L

Rasche, L (corresponding author), Univ Hosp Wurzburg, Dept Internal Med 2, Wurzburg, Germany.; Rasche, L (corresponding author), Univ Hosp Wurzburg, Mildred Scheel Early Career Ctr, Wurzburg, Germany.

NATURE MEDICINE, ; ():

Abstract

B cell maturation antigen (BCMA) is a target for various immunotherapies and a biomarker for tumor load in multiple myeloma (MM). We report a case of ......

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