Synthesis, Stability, and Anti-Tumour Activity of a New Category of "Stapled" Antisense Oligonucleotides with Stimuli-Responsive Feature

Ren, HQ; Song, LY; Zhang, W; Xu, L

Xu, L (corresponding author), Beijing Inst Pharmacol & Toxicol, State Key Lab Toxicol & Med Countermeasures, Beijing, Peoples R China.

JOURNAL OF PHARMACEUTICAL SCIENCES, 2021; 110 (9): 3166

Abstract

The development of nucleic acid drugs with unique structures and mechanisms has stimulated great research interest. Herein, we report a general strate......

Full Text Link