Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Tominaga, K; Shimamura, T; Kimura, N; Murayama, T; Matsubara, D; Kanauchi, H; Niida, A; Shimizu, S; Nishioka, K; Tsuji, EI; Yano, M; Sugano, S; Shimono, Y; Ishii, H; Saya, H; Mori, M; Akashi, K; Tada, KI; Ogawa, T; Tojo, A; Miyano, S; Gotoh, N

Gotoh, N (reprint author), Univ Tokyo, Inst Med Sci, Div Mol Therapy, Minato Ku, 4-6-1 Shirokanedai, Tokyo, Japan.; Gotoh, N (reprint author), Kanazawa Univ, Canc Res Inst, Div Canc Cell Biol, Kakuma Machi, Kanazawa, Ishikawa 9201192, Japan.

ONCOGENE, 2017; 36 (9): 1276

Abstract

The transcription factor nuclear factor-kappa B (NF-kappa B) has important roles for tumorigenesis, but how it regulates cancer stem cells (CSCs) rema......

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