Pro-tumor Tfh2 cells induce detrimental IgG4 production and PGE2-dependent IgE inhibition in pancreatic cancer

De Monte, L; Clemente, F; Ruggiero, E; Pini, R; Ceraolo, MG; Lena, MS; Balestrieri, C; Lazarevic, D; Bel, G; Crippa, S; Balzano, G; Falconi, M; Doglioni, C; Bonini, C; Reni, M; Protti, MP

Protti, MP (通讯作者)，Ist Sci San Raffaele, Div Immunol Transplantat & Infect Dis, Tumor Immunol Unit, Via Olgettina 58, I-20132 Milan, Italy.

EBIOMEDICINE, 2023; 97 ():

Abstract

Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis and it is characterized by predominant pro-tumor Th2-type inflammation. T fo......

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