Laboratory Variants GES(G170L), GES(G170K), and GES(G170H) Increase Carbapenem Hydrolysis and Confer Resistance to Clavulanic Acid

Piccirilli, A; Mercuri, PS; Segatore, B; Galleni, M; Brisdelli, F; Kerff, F; Amicosante, G; Perilli, M

Piccirilli, A; Perilli, M (corresponding author), Univ Aquila, Dipartimento Sci Clin Applicate & Biotecnol, Laquila, Italy.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021; 65 (6):

Abstract

The Guiana extended-spectrum (GES) beta-lactamase GES(G170H), GES(G170L), and GES(G170K) mutants showed k(cat), K-m, and k(cat)/K-m values very dissim......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索