Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1)

Yu, J; Zhong, BL; Zhao, L; Hou, Y; Wang, XZ; Chen, XP

Chen, XP (corresponding author), Univ Macau, Inst Chinese Med Sci, Ave Univ, Taipa, Macau, Peoples R China.

FREE RADICAL BIOLOGY AND MEDICINE, 2021; 173 (): 64

Abstract

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) has been identified as a critical mediator of cell death (necroptosis and apoptosis) an......

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