Wnt/IL-1 beta/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5

Milosevic, V; Kopecka, J; Salaroglio, IC; Libener, R; Napoli, F; Izzo, S; Orecchia, S; Ananthanarayanan, P; Bironzo, P; Grosso, F; Tabbo, F; Comunanza, V; Alexa-Stratulat, T; Bussolino, F; Righi, L; Novello, S; Scagliotti, GV; Riganti, C

INTERNATIONAL JOURNAL OF CANCER, 2020; 146 (1): 192

Abstract

Malignant pleural mesothelioma (MPM) is a tumor with high chemoresistance and poor prognosis. MPM-initiating cells (ICs) are known to be drug resistan......

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