The cation-pi interaction in cysteine-rich domain of Smoothened is critical for its cholesterylation and function

Kong, ZK; Xu, M; Zhang, YQ; Huang, WD; Zhao, XL; Luo, J; Song, BL

Song, BL (通讯作者),Wuhan Univ, TaiKang Med Sch, TaiKang Ctr Life & Med Sci, Coll Life Sci,Hubei Key Lab Cell Homeostasis, Wuhan 430071, Peoples R China.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022; 54 (8): 1171

Abstract

The Hedgehog (Hh) signaling pathway is critical for embryonic development and tissue renewal. The G protein-coupled receptor (GPCR)-like protein Smoot......

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