Scalable Synthesis of Both Enantiomers of Vigabatrin, an Antiepileptic Drug

Jachak, GR; Reddy, DS

Reddy, DS (reprint author), CSIR Natl Chem Lab, Organ Chem Div, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India.; Reddy, DS (reprint author), Acad Sci & Innovat Res AcSIR, New Delhi 110025, India.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2019; 2019 (6): 1257

Abstract

Vigabatrin is a potent inhibitor of gamma-aminobutyric acid (GABA) catabolism used for the treatment of epilepsy. Here we have synthesized both enanti......

Full Text Link