Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

Vijay, R; Guthmiller, JJ; Sturtz, AJ; Surette, FA; Rogers, KJ; Sompallae, RR; Li, FY; Pope, RL; Chan, JA; Rivera, FD; Andrew, D; Webb, L; Maury, WJ; Xue, HH; Engwerda, CR; McCarthy, JS; Boyle, MJ; Butler, NS

Butler, NS (corresponding author), Univ Iowa, Dept Microbiol & Immunol, Iowa City, IA 52242 USA.; Butler, NS (corresponding author), Univ Oklahoma, Hlth Sci Ctr, Dept Microbiol & Immunol, Oklahoma City, OK 73190 USA.; Butler, NS (corresponding author), Univ Iowa, Interdisciplinary Grad Program Immunol, Iowa City, IA 52242 USA.

NATURE IMMUNOLOGY, 2020; 21 (7): 790

Abstract

Plasmodium parasite-specific antibodies are critical for protection against malaria, yet the development of long-lived and effective humoral immunity ......

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